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Characteristics
|
Cases (n = 32)
|
Controls (n = 64)
|
P value
|
|---|
|
Age (yr), mean ± SD
|
81 ± 5
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81 ± 5
|
NS
|
|
Gender, M/F
|
14/18
|
28/36
|
NS
|
|
PT-INR
| | | |
|
Median PT-INR(Q1,Q3)
|
2.62 (1.97, 5.30)
|
1.75 (1.52, 2.14)
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<0.05
|
|
≤1.49, n (%)
|
5 (16)
|
15 (24)
|
NS
|
|
1.50 to 1.99, n (%)
|
3 (9)
|
29 (45)
|
<0.05
|
|
2.00 to 2.49, n (%)
|
5 (16)
|
13 (20)
|
NS
|
|
2.50 to 2.99, n (%)
|
4 (12)
|
6 (9)
|
NS
|
|
≥3.00, n (%)
|
15 (47)
|
1 (2)
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<0.05
|
|
eGFR (mL/min/1.73 m2), mean ± SD
|
43 ± 27
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49 ± 15
|
NS
|
|
CHADS2 score, mean ± SD
|
3 ± 1
|
3 ± 1
|
NS
|
|
Congestive heart failure, n (%)
|
19 (59)
|
19 (30)
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<0.05
|
|
Hypertension, n (%)
|
22 (69)
|
50 (78)
|
NS
|
|
Diabetes, n (%)
|
5 (16)
|
21 (33)
|
NS
|
|
Stroke/TIA, n (%)
|
16 (50)
|
23 (36)
|
NS
|
|
HAS-BLED score, mean ± SD
|
3 ± 1
|
3 ± 1
|
NS
|
|
Impaired renal function, n (%)
|
7 (22)
|
3 (5)
|
<0.05
|
|
Impaired liver function, n (%)
|
4 (13)
|
3 (5)
|
NS
|
|
Stroke, n (%)
|
14 (44)
|
22 (34)
|
NS
|
|
History of bleeding, n (%)
|
10 (31)
|
14 (22)
|
NS
|
|
Labile PT-INR, n (%)
|
2 (6)
|
19 (30)
|
NS
|
|
Antiplatelet or NSAID, n (%)
|
12 (38)
|
24 (38)
|
NS
|
|
Alcohol consumption, n (%)
|
1 (3)
|
4 (6)
|
NS
|
- Q1 and 3 represent the upper limits of the first and third interquartile ranges. TIA transient ischemic attack, PT-INR prothrombin time-international normalized ratio, eGFR estimated glomerular filtration rate, NSAID non-steroidal anti-inflammatory drug
