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Table 3 Comparison of the incidence of adverse events between the prophylactic and regular groups in the entire study population

From: Safety profile of prophylactic rescue dosing of immediate-release oral opioids in cancer patients

Adverse event Prophylactic rescue Regular rescue P value
n = 68 n = 35
Somnolence, n (%) 14 (20.6) 5 (14.3) 0.59a
Nausea, n (%) 15 (22.1) 6 (17.1) 0.62a
Constipation, n (%) 13 (19.1) 7 (20.0) 1.00a
Urinary retention, n (%) 1 (1.5) 1 (2.9) 1.00a
Delirium, n (%) 3 (4.4) 3 (8.6) 0.40a
Pruritus, n (%) 0 (0) 1 (2.9) 0.34a
  1. aFisher’s exact test