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Table 4 Comparison of the incidence of adverse events between the prophylactic and regular groups in the morphine subgroup

From: Safety profile of prophylactic rescue dosing of immediate-release oral opioids in cancer patients

Adverse event Prophylactic morphine Regular morphine P value
n = 38 n = 14
Somnolence, n (%) 6 (15.8) 2 (14.3) 1.00a
Nausea, n (%) 10 (26.3) 4 (28.6) 1.00a
Constipation, n (%) 12 (31.6) 4 (28.6) 1.00a
Urinary retention, n (%) 0 (0) 1 (7.1) 0.27a
Delirium, n (%) 2 (5.3) 1 (7.1) 1.00a
Pruritus, n (%) 0 (0) 1 (7.1) 0.27a
  1. aFisher’s exact test