From: Safety profile of prophylactic rescue dosing of immediate-release oral opioids in cancer patients
| Adverse event | Prophylactic morphine | Regular morphine | P value |
|---|---|---|---|
| n = 38 | n = 14 | ||
| Somnolence, n (%) | 6 (15.8) | 2 (14.3) | 1.00a |
| Nausea, n (%) | 10 (26.3) | 4 (28.6) | 1.00a |
| Constipation, n (%) | 12 (31.6) | 4 (28.6) | 1.00a |
| Urinary retention, n (%) | 0 (0) | 1 (7.1) | 0.27a |
| Delirium, n (%) | 2 (5.3) | 1 (7.1) | 1.00a |
| Pruritus, n (%) | 0 (0) | 1 (7.1) | 0.27a |